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Blue Lotus: Difference between revisions

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>Cmspeedrunner
Created page with "'''''Nymphaea nouchali'' var. ''caerulea''''' (Commonly known as '''Blue Lotus''') is a water lily found throughout most of the eastern half of Africa. <br /> {{SubstanceBox..."
>ElectricVeg
change image to verified source; fixed image formatting
 
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'''''Nymphaea nouchali'' var. ''caerulea''''' (Commonly known as '''Blue Lotus''') is a water lily found throughout most of the eastern half of Africa.
'''''Nymphaea nouchali'' var. ''caerulea''''' (Commonly known as '''Blue Lotus''') is a water lily found throughout most of the eastern half of Africa.
<br />
{{SubstanceBox
{{SubstanceBox


     <!-- Special Parameters -->
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     |ModuleStructure=true
     |ModuleStructure=true
     |ModuleNomenclature=true
     |ModuleNomenclature=true
    |ModuleClassMembership=true
     |ModuleROA=true
     |ModuleROA=true


     <!-- Source -->
     <!-- Source -->
     |PhotoImageFile=[[File:BlueLotus.jpg|thumb]]
     |PhotoImageFile=  
     |PhotoImageWidth=
     |PhotoImageWidth=
     |PhotoImageCaption=
     |PhotoImageCaption=
Line 35: Line 34:


     <!-- Structure -->
     <!-- Structure -->
    |MolecularStructureCaption=Aporphine
     |SkeletalImageFile=File:Plate-8-nymphaea-caerulea.png
     |SkeletalImageFile=
     |SkeletalImageWidth=245px
     |SkeletalImageWidth=
     |3DImageFile=
     |3DImageFile=
     |3DImageWidth=
     |3DImageWidth=


      
     <!-- Nomenclature -->
     |NameCommon=
     |NameCommon=[[Blue Lotus]], [[Nymphaea nouchali var. caerulea]], [[Lotus]]
     |NameSubstitution=
     |NameSubstitution=
     |NameSystematic=
     |NameSystematic=


     <!-- Dosage/Duration per ROA -->
     <!-- Class Membership -->
    |EffectClass=[[Sedative]]
    |ChemicalClass=[[Morphinans]]
 
    <!-- Dosage/Duration per ROA -->


     |SmokedROA=true
     |SmokedROA=true
     |SmokedROA_Collapsed=true
     |SmokedROA_Collapsed=false
     |SmokedROA_Caption=
     |SmokedROA_Caption=  
     |SmokedROA_Bioavailability=
     |SmokedROA_Bioavailability=
     |SmokedROA_Threshold=< x mg
    |SmokedROA_Microdose=
     |SmokedROA_Light=x - x mg
     |SmokedROA_Threshold=[[Smoked threshold dose::0.5]] -  [[Smoked dose units::g]]
     |SmokedROA_Common=x - x mg
     |SmokedROA_Light=[[Smoked min light dose::0.75]] - [[Smoked max light dose::1]] g
     |SmokedROA_Strong=x - x mg
     |SmokedROA_Common=[[Smoked min common dose::1.25]] - [[Smoked max common dose::2]] g
     |SmokedROA_Heavy= >  mg
     |SmokedROA_Strong=[[Smoked min strong dose::2.5]] - [[Smoked max strong dose::3]] g
     |SmokedROA_Heavy=[[Smoked heavy dose::5]] g +
     |SmokedROA_TimelineFile=
     |SmokedROA_TimelineFile=
     |SmokedROA_TimelineWidth=
     |SmokedROA_TimelineWidth=
     |SmokedROA_Duration=x - x hours
     |SmokedROA_Duration=[[Oral min total time::6]] - [[Oral max total time::8]] [[Oral total time units::hours]]
     |SmokedROA_Onset=x minutes
     |SmokedROA_Onset=[[Oral min onset time::10]] - [[Oral max onset time::60]] [[Oral onset time units::seconds]]
    |SmokedROA_Peak=x hours
     |SmokedROA_Comeup=[[Oral min comeup time::5]] - [[Oral max comeup time::10]] [[Oral comeup time units::minutes]]
    |SmokedROA_Offset=x hours
     |SmokedROA_Peak=[[Oral min peak time::1]] - [[Oral max peak time::2]] [[Oral peak time units::hours]]
    |SmokedROA_Aftereffects=x hours
     |SmokedROA_Offset=[[Oral min offset time::2]] - [[Oral max offset time::2.5]] [[Oral offset time units::hours]]
 
     |SmokedROA_Aftereffects=[[Oral min afterglow time::6]] - [[Oral max afterglow time::8]] [[Oral afterglow time units::hours]]
    |OralROA=true
    |OralROA_Collapsed=true
    |OralROA_Caption=
    |OralROA_Bioavailability=
    |OralROA_Threshold=< x mg
    |OralROA_Light=x - x mg
     |OralROA_Common=x - x mg
     |OralROA_Strong=x - x mg
     |OralROA_Heavy= >  mg
    |OralROA_TimelineFile=
    |OralROA_TimelineWidth=
    |OralROA_Duration=x - x hours
     |OralROA_Onset=x minutes
    |OralROA_Peak=x hours
    |OralROA_Offset=x hours
    |OralROA_Aftereffects=x hours


     |SublingualROA=false
     |SublingualROA=false
     |SublingualROA_Collapsed=true
     |SublingualROA_Collapsed=true
     |SublingualROA_Caption=
     |SublingualROA_Caption=
     |SublingualROA_Bioavailability=
     |SublingualROA_Bioavailability=[[Sublingual min bioavailability::x]]% - [[Sublingual max bioavailability::y]]%
     |SublingualROA_Threshold=< x mg
    |SublingualROA_Microdose=
     |SublingualROA_Light=x - x mg
     |SublingualROA_Threshold=[[Sublingual threshold dose::x]] - [[Sublingual dose units::mg]]
     |SublingualROA_Common=x - x mg
     |SublingualROA_Light=[[Sublingual min light dose::x]] - [[Sublingual max light dose::y]] mg
     |SublingualROA_Strong=x - x mg
     |SublingualROA_Common=[[Sublingual min common dose::x]] - [[Sublingual max common dose::y]] mg
     |SublingualROA_Heavy= >  mg
     |SublingualROA_Strong=[[Sublingual min strong dose::x]] - [[Sublingual max strong dose::y]] mg
     |SublingualROA_Heavy=[[Sublingual heavy dose::x]] mg +
     |SublingualROA_TimelineFile=
     |SublingualROA_TimelineFile=
     |SublingualROA_TimelineWidth=
     |SublingualROA_TimelineWidth=
     |SublingualROA_Duration=x - x hours
     |SublingualROA_Duration=[[Sublingual min total time::a]] - [[Sublingual max total time::b]] [[Sublingual total time units::hours]]
     |SublingualROA_Onset=x minutes
    |SublingualROA_Onset=[[Sublingual min onset time::a]] - [[Sublingual max onset time::b]] [[Sublingual onset time units::minutes]]
     |SublingualROA_Peak=x hours
    |SublingualROA_Comeup=[[Sublingual min comeup time::a]] - [[Sublingual max comeup time::b]] [[Sublingual comeup time units::minutes]]
     |SublingualROA_Offset=x hours
    |SublingualROA_Peak=[[Sublingual min peak time::a]] - [[Sublingual max peak time::b]] [[Sublingual peak time units::hours]]
     |SublingualROA_Aftereffects=x hours
    |SublingualROA_Offset=[[Sublingual min offset time::a]] - [[Sublingual max offset time::b]] [[Sublingual offset time units::hours]]
    |SublingualROA_Aftereffects=[[Sublingual min afterglow time::a]] - [[Sublingual max afterglow time::b]] [[Sublingual afterglow time units::hours]]
 
    |BuccalROA=false
    |BuccalROA_Collapsed=True
    |BuccalROA_Caption=
    |BuccalROA_Bioavailability=[[Buccal min bioavailability::x]]% - [[Buccal max bioavailability::y]]%<ref>APA formatted citation</ref>
    |BuccalROA_Microdose=
    |BuccalROA_Threshold=[[Buccal threshold dose::x]] -  [[Buccal dose units::mg]]
    |BuccalROA_Light=[[Buccal min light dose::x]] - [[Buccal max light dose::y]] mg
    |BuccalROA_Common=[[Buccal min common dose::x]] - [[Buccal max common dose::y]] mg
    |BuccalROA_Strong=[[Buccal min strong dose::x]] - [[Buccal max strong dose::y]] mg
    |BuccalROA_Heavy=[[Buccal heavy dose::x]] mg +
    |BuccalROA_TimelineFile=
    |BuccalROA_TimelineWidth=
    |BuccalROA_Duration=[[Buccal min total time::x]] - [[Buccal max total time::y]] [[Buccal total time units::hours]]
    |BuccalROA_Onset=[[Buccal min onset time::x]] - [[Buccal max onset time::y]] [[Buccal onset time units::minutes]]
    |BuccalROA_Comeup=[[Buccal min comeup time::x]] - [[Buccal max comeup time::y]] [[Buccal comeup time units::minutes]]
    |BuccalROA_Peak=[[Buccal min peak time::x]] - [[Buccal max peak time::y]] [[Buccal peak time units::hours]]
    |BuccalROA_Offset=[[Buccal min offset time::x]] - [[Buccal max offset time::y]] [[Buccal offset time units::hours]]
    |BuccalROA_Aftereffects=[[Buccal min afterglow time::x]] - [[Buccal max afterglow time::y]] [[Buccal afterglow time units::hours]]
 
    |InsufflatedROA=false
    |InsufflatedROA_Collapsed=True
    |InsufflatedROA_Caption=
    |InsufflatedROA_Bioavailability=[[Insufflated min bioavailability::x]]% - [[Insufflated max bioavailability::y]]%<ref>APA formatted citation</ref>
    |InsufflatedROA_Microdose=
    |InsufflatedROA_Threshold=[[Insufflated threshold dose::x]] -  [[Insufflated dose units::mg]]
    |InsufflatedROA_Light=[[Insufflated min light dose::x]] - [[Insufflated max light dose::y]] mg
    |InsufflatedROA_Common=[[Insufflated min common dose::x]] - [[Insufflated max common dose::y]] mg
    |InsufflatedROA_Strong=[[Insufflated min strong dose::x]] - [[Insufflated max strong dose::y]] mg
    |InsufflatedROA_Heavy=[[Insufflated heavy dose::x]] mg +
    |InsufflatedROA_TimelineFile=
    |InsufflatedROA_TimelineWidth=
    |InsufflatedROA_Duration=[[Insufflated min total time::x]] - [[Insufflated max total time::y]] [[Insufflated total time units::hours]]
    |InsufflatedROA_Onset=[[Insufflated min onset time::x]] - [[Insufflated max onset time::y]] [[Insufflated onset time units::minutes]]
    |InsufflatedROA_Comeup=[[Insufflated min comeup time::x]] - [[Insufflated max comeup time::y]] [[Insufflated comeup time units::minutes]]
    |InsufflatedROA_Peak=[[Insufflated min peak time::x]] - [[Insufflated max peak time::y]] [[Insufflated peak time units::hours]]
    |InsufflatedROA_Offset=[[Insufflated min offset time::x]] - [[Insufflated max offset time::y]] [[Insufflated offset time units::hours]]
    |InsufflatedROA_Aftereffects=[[Insufflated min afterglow time::x]] - [[Insufflated max afterglow time::y]] [[Insufflated afterglow time units::hours]]
 
     |RectalROA=false
    |RectalROA_Collapsed=True
    |RectalROA_Caption=
    |RectalROA_Bioavailability=[[Rectal min bioavailability::x]]% - [[Rectal max bioavailability::y]]
    |RectalROA_Microdose=
    |RectalROA_Threshold=[[Rectal threshold dose::x]] -  [[Rectal dose units::mg]]
    |RectalROA_Light=[[Rectal min light dose::x]] - [[Rectal max light dose::y]] mg
    |RectalROA_Common=[[Rectal min common dose::x]] - [[Rectal max common dose::y]] mg
    |RectalROA_Strong=[[Rectal min strong dose::x]] - [[Rectal max strong dose::y]] mg
    |RectalROA_Heavy=[[Rectal heavy dose::x]] mg +
    |RectalROA_TimelineFile=
    |RectalROA_TimelineWidth=
    |RectalROA_Duration=[[Rectal min total time::x]] - [[Rectal max total time::y]] [[Rectal total time units::hours]]
    |RectalROA_Onset=[[Rectal min onset time::x]] - [[Rectal max onset time::y]] [[Rectal onset time units::minutes]]
    |RectalROA_Comeup=[[Rectal min comeup time::x]] - [[Rectal max comeup time::y]] [[Rectal comeup time units::minutes]]
     |RectalROA_Peak=[[Rectal min peak time::x]] - [[Rectal max peak time::y]] [[Rectal peak time units::hours]]
     |RectalROA_Offset=[[Rectal min offset time::x]] - [[Rectal max offset time::y]] [[Rectal offset time units::hours]]
     |RectalROA_Aftereffects=[[Rectal min afterglow time::x]] - [[Rectal max afterglow time::y]] [[Rectal afterglow time units::hours]]


     |TransdermalROA=false
     |TransdermalROA=false
     |TransdermalROA_Collapsed=true
     |TransdermalROA_Collapsed=True
     |TransdermalROA_Caption=Presumes no tolerance
     |TransdermalROA_Caption=
     |TransdermalROA_Bioavailability=
     |TransdermalROA_Bioavailability=[[Transdermal min bioavailability::x]]% - [[Transdermal max bioavailability::y]]%<ref>APA formatted citation</ref>
     |TransdermalROA_Threshold=< x mg
    |TransdermalROA_Microdose=
     |TransdermalROA_Light=x - x mg
     |TransdermalROA_Threshold=[[Transdermal threshold dose::x]] -  [[Transdermal dose units::mg]]
     |TransdermalROA_Common=x - x mg
     |TransdermalROA_Light=[[Transdermal min light dose::x]] - [[Transdermal max light dose::y]] mg
     |TransdermalROA_Strong=x - x mg
     |TransdermalROA_Common=[[Transdermal min common dose::x]] - [[Transdermal max common dose::y]] mg
     |TransdermalROA_Heavy= >  mg
     |TransdermalROA_Strong=[[Transdermal min strong dose::x]] - [[Transdermal max strong dose::y]] mg
     |TransdermalROA_Heavy=[[Transdermal heavy dose::x]] mg +
     |TransdermalROA_TimelineFile=
     |TransdermalROA_TimelineFile=
     |TransdermalROA_TimelineWidth=
     |TransdermalROA_TimelineWidth=
     |TransdermalROA_Duration=x - x hours
     |TransdermalROA_Duration=[[Transdermal min total time::x]] - [[Transdermal max total time::y]] [[Transdermal total time units::hours]]
     |TransdermalROA_Onset=x minutes
     |TransdermalROA_Onset=[[Transdermal min onset time::x]] - [[Transdermal max onset time::y]] [[Transdermal onset time units::minutes]]
     |TransdermalROA_Peak=x hours
    |TransdermalROA_Comeup=[[Transdermal min comeup time::x]] - [[Transdermal max comeup time::y]] [[Transdermal comeup time units::minutes]]
     |TransdermalROA_Offset=x hours
     |TransdermalROA_Peak=[[Transdermal min peak time::x]] - [[Transdermal max peak time::y]] [[Transdermal peak time units::hours]]
     |TransdermalROA_Aftereffects=x hours
     |TransdermalROA_Offset=[[Transdermal min offset time::x]] - [[Transdermal max offset time::y]] [[Transdermal offset time units::hours]]
     |TransdermalROA_Aftereffects=[[Transdermal min afterglow time::x]] - [[Transdermal max afterglow time::y]] [[Transdermal afterglow time units::hours]]


     |SubcutaneousROA=false
     |SubcutaneousROA=false
     |SubcutaneousROA_Collapsed=true
     |SubcutaneousROA_Collapsed=True
     |SubcutaneousROA_Caption=Presumes no tolerance
     |SubcutaneousROA_Caption=
     |SubcutaneousROA_Bioavailability=
     |SubcutaneousROA_Bioavailability=[[Subcutaneous min bioavailability::x]]% - [[Subcutaneous max bioavailability::y]]%<ref>APA formatted citation</ref>
     |SubcutaneousROA_Threshold=< x mg
    |SubcutaneousROA_Microdose=
     |SubcutaneousROA_Light=x - x mg
     |SubcutaneousROA_Threshold=[[Subcutaneous threshold dose::x]] -  [[Subcutaneous dose units::mg]]
     |SubcutaneousROA_Common=x - x mg
     |SubcutaneousROA_Light=[[Subcutaneous min light dose::x]] - [[Subcutaneous max light dose::y]] mg
     |SubcutaneousROA_Strong=x - x mg
     |SubcutaneousROA_Common=[[Subcutaneous min common dose::x]] - [[Subcutaneous max common dose::y]] mg
     |SubcutaneousROA_Heavy= >  mg
     |SubcutaneousROA_Strong=[[Subcutaneous min strong dose::x]] - [[Subcutaneous max strong dose::y]] mg
     |SubcutaneousROA_Heavy=[[Subcutaneous heavy dose::x]] mg +
     |SubcutaneousROA_TimelineFile=
     |SubcutaneousROA_TimelineFile=
     |SubcutaneousROA_TimelineWidth=
     |SubcutaneousROA_TimelineWidth=
     |SubcutaneousROA_Duration=x - x hours
     |SubcutaneousROA_Duration=[[Subcutaneous min total time::x]] - [[Subcutaneous max total time::y]] [[Subcutaneous total time units::hours]]
     |SubcutaneousROA_Onset=x minutes
     |SubcutaneousROA_Onset=[[Subcutaneous min onset time::x]] - [[Subcutaneous max onset time::y]] [[Subcutaneous onset time units::minutes]]
     |SubcutaneousROA_Peak=x hours
    |SubcutaneousROA_Comeup=[[Subcutaneous min comeup time::x]] - [[Subcutaneous max comeup time::y]] [[Subcutaneous comeup time units::minutes]]
     |SubcutaneousROA_Offset=x hours
     |SubcutaneousROA_Peak=[[Subcutaneous min peak time::x]] - [[Subcutaneous max peak time::y]] [[Subcutaneous peak time units::hours]]
     |SubcutaneousROA_Aftereffects=x hours
     |SubcutaneousROA_Offset=[[Subcutaneous min offset time::x]] - [[Subcutaneous max offset time::y]] [[Subcutaneous offset time units::hours]]
     |SubcutaneousROA_Aftereffects=[[Subcutaneous min afterglow time::x]] - [[Subcutaneous max afterglow time::y]] [[Subcutaneous afterglow time units::hours]]


     }}
     |IntramuscularROA=false
    |IntramuscularROA_Collapsed=true
    |IntramuscularROA_Caption=
    |IntramuscularROA_Bioavailability=[[Intramuscular min bioavailability::x]]% - [[Intramuscular max bioavailability::y]]%<ref>APA formatted citation</ref>
    |IntramuscularROA_Microdose=
    |IntramuscularROA_Threshold=[[Intramuscular threshold dose::x]] -  [[Intramuscular dose units::mg]]
    |IntramuscularROA_Light=[[Intramuscular min light dose::x]] - [[Intramuscular max light dose::y]] mg
    |IntramuscularROA_Common=[[Intramuscular min common dose::x]] - [[Intramuscular max common dose::y]] mg
    |IntramuscularROA_Strong=[[Intramuscular min strong dose::x]] - [[Intramuscular max strong dose::y]] mg
    |IntramuscularROA_Heavy=[[Intramuscular heavy dose::x]] mg +
    |IntramuscularROA_TimelineFile=
    |IntramuscularROA_TimelineWidth=
    |IntramuscularROA_Duration=[[Intramuscular min total time::x]] - [[Intramuscular max total time::y]] [[Intramuscular total time units::hours]]
    |IntramuscularROA_Onset=[[Intramuscular min onset time::x]] - [[Intramuscular max onset time::y]] [[Intramuscular onset time units::minutes]]
    |IntramuscularROA_Comeup=[[Intramuscular min comeup time::x]] - [[Intramuscular max comeup time::y]] [[Intramuscular comeup time units::minutes]]
    |IntramuscularROA_Peak=[[Intramuscular min peak time::x]] - [[Intramuscular max peak time::y]] [[Intramuscular peak time units::hours]]
    |IntramuscularROA_Offset=[[Intramuscular min offset time::x]] - [[Intramuscular max offset time::y]] [[Intramuscular offset time units::hours]]
    |IntramuscularROA_Aftereffects=[[Intramuscular min afterglow time::x]] - [[Intramuscular max afterglow time::y]] [[Intramuscular afterglow time units::hours]]


    |IntravenousROA=false
    |IntravenousROA_Collapsed=true
    |IntravenousROA_Caption=
    |IntravenousROA_Bioavailability=[[Intravenous min bioavailability::x]]% - [[Intravenous max bioavailability::y]]%<ref>APA formatted citation</ref>
    |IntravenousROA_Microdose=
    |IntravenousROA_Threshold=[[Intravenous threshold dose::x]] -  [[Intravenous dose units::mg]]
    |IntravenousROA_Light=[[Intravenous min light dose::x]] - [[Intravenous max light dose::y]] mg
    |IntravenousROA_Common=[[Intravenous min common dose::x]] - [[Intravenous max common dose::y]] mg
    |IntravenousROA_Strong=[[Intravenous min strong dose::x]] - [[Intravenous max strong dose::y]] mg
    |IntravenousROA_Heavy=[[Intravenous heavy dose::x]] mg +
    |IntravenousROA_TimelineFile=
    |IntravenousROA_TimelineWidth=
    |IntravenousROA_Duration=[[Intravenous min total time::x]] - [[Intravenous max total time::y]] [[Intravenous total time units::hours]]
    |IntravenousROA_Onset=[[Intravenous min onset time::x]] - [[Intravenous max onset time::y]] [[Intravenous onset time units::minutes]]
    |IntravenousROA_Comeup=[[Intravenous min comeup time::x]] - [[Intravenous max comeup time::y]] [[Intravenous comeup time units::minutes]]
    |IntravenousROA_Peak=[[Intravenous min peak time::x]] - [[Intravenous max peak time::y]] [[Intravenous peak time units::hours]]
    |IntravenousROA_Offset=[[Intravenous min offset time::x]] - [[Intravenous max offset time::y]] [[Intravenous offset time units::hours]]
    |IntravenousROA_Aftereffects=[[Intravenous min afterglow time::x]] - [[Intravenous max afterglow time::y]] [[Intravenous afterglow time units::hours]]


[[Subjective effects]] include [[Color enhancement]], [[Sedation]], [[Pain relief]], [[Dream potentiation]], [[Dizziness]], [[Nausea]] and [[Increased music appreciation]].
}}


Like other species in the genus, the plant contains the psychoactive alkaloid [[aporphine]] which is thought to be the main constituent causing the effects of the flower, however, it is more likely a group of aporphine alkaloids are working in conjunction to create the various effects as opposed to
The flower has been used for over 2000 years in teas, herbal blends and in perfumes.


just aporphine.
Like other species in the genus, the plant contains the psychoactive alkaloid [[aporphine]] which is thought to be the main constituent causing the effects of the flower, however, it is more likely a group of aporphine alkaloids are working in conjunction to create the various effects as opposed to just aporphine. High potent extracts when ingested or smoked in high doses are reported to produce [[euphoria]] and [[Hallucination|hallucinations]].  


==History and culture==
==History and culture==
The first description of Blue Lotus appears in 1798, however Blue Lotus is thought to be the primary for the fruit of the lotus tree eaten by the mythical Lotophagi (Lotus Eaters) in Homer's ''Odyssey.''
Blue Lotus is thought to be the primary for the fruit of the lotus tree eaten by the mythical Lotophagi (Lotus Eaters) in Homer's ''Odyssey.'' The Lotus Eaters were a race of people living on an island dominated by the lotus tree, after they ate the lotus, they would forget their home and loved ones and long only to stay with their fellow lotus-eaters, falling into a infinite euphoric stupor. Those who ate the plant never cared to report or return.


This lotus has been used to produce perfumes since egyptian times. According to a 2023 preprint study, traces of ''[[Peganum harmala]]'', and Blue Lotus were identified in an Egyptian ritual Bes-vase, of the 2nd century BCE
This lotus has been used to produce perfumes since egyptian times. According to a 2023 preprint study, traces of ''[[Peganum harmala]]'', and Blue Lotus were identified in an Egyptian ritual Bes-vase, of the 2nd century BCE


The plant and flower are very prominent and frequent in Ancient Egyptian art
The plant and flower are very prominent and frequent in Ancient Egyptian art, cuisine and perfumes.
==Chemistry==
The plant has been found to contain [[aporphine]] and similar alkaloids as well as Nuciferine. The effects of Blue Lotus are thought to be down to these compounds but other various Quinoline alkaloids could play a role.
 
==Pharmacology==
[[aporphine]], thought to be the main active component, dopamine receptor agonist targeting the D1 and D2 receptors. Nuciferine, also a prominent alkaloid, is an antagonist at [[5-HT2A receptor|5-HT<sub>2A</sub>]], 5-HT<sub>2C</sub>, and 5-HT<sub>2B</sub> receptors, but is also a partial agonist at D2, D5, and 5-HT<sub>6</sub> receptors, and an [[agonist]] at 5-HT<sub>1A</sub> and D4 receptors. Additionally, it inhibits the dopamine transporter (DAT).
 
[[Apomorphine]], the active metabolite of Aporphine, has a catechol structure similar to that of dopamine.
 
==Subjective effects==
{{Preamble/SubjectiveEffects}}
 
{{effects/base
 
|{{effects/physical|
Blue Lotus most potent effects are the sedation and muscle relaxation it causes. This leads many to use it as a sleep aid or lucid dreaming aid.
 
You may select physical effects to add below [[Subjective effect index#Physical effects|here]].
 
*'''[[Effect::Pain relief]]'''
*'''[[Effect::Sedation]]'''
*'''[[Effect::Muscle relaxation]]'''
*'''[[Effect::Headache]]'''
*'''[[Effect::Nausea]]'''
 
 
 
}}
{{effects/visual|
While subtle, if enough is ingested (Most often through smoking), Blue Lotus can cause visual effects and enhancements.
 
You may select visual effects to add below [[Subjective effect index#Visual effects|here]].
 
====Enhancements====
*'''[[Effect::Visual Color enhancement]]'''
 
====Distortions====
*'''[[Effect::Visual Tracers]]'''
*'''[[Effect::Brightness alteration]]'''
 
}}
 
|{{effects/cognitive|
Blue Lotus has most of its cognitive effects manifest themself in sleep. This leads many to use it as a sleep aid or lucid dreaming aid.
 
You may select from a list of cognitive effects to add below [[Subjective effect index#Cognitive effects|here]].
 
*'''[[Effect::Increased music appreciation]]'''
*'''[[Effect::Empathy, affection, and sociability enhancement]]'''
*'''[[Effect::Dream potentiation]]'''
*'''[[Effect::Derealization]]'''
*'''[[Effect::Sleepiness]]'''
*'''[[Effect::Disinhibition]]'''
*'''[[Effect::Focus suppression]]'''
 
}}
{{effects/auditory|
Blue Lotus most prominent auditory effect is the enhancement of music. This can be described as the music sounding sharper or more clear.
 
You may select from a list of auditory effects to add below [[Subjective effect index#Auditory effects|here]].
 
*'''[[Effect::Auditory acuity enhancement]]'''
 
 
}}
 
 
}}
===Experience reports===
{{Experience reports|Blue Lotus|https://www.erowid.org/experiences/subs/exp_Lotus_I_Lily_Group.shtml}} <!-- Check the link to see if it exists -->
 
==Toxicity and harm potential==
The toxicity of Blue Lotus is misunderstood and poorly researched. Only the pure alkaloids have been tested with little toxicity, however, mixing Blue Lotus with other substances could present a risk.
 
It is strongly recommended that one use [[responsible use|harm reduction practices]] when using this substance.
===Lethal dosage===
There are no studies on aporphine in animals. However, studies on subcutaneous apomorphine injection, the bioactive form of aporphine, have been carried out. In a 5-day study, mice were administered up to 10 mg/kg apomorphine subcutaneously daily. No adverse effects were observed other than a slight increase in dopamine levels.
 
===Tolerance and addiction potential===
Blue Lotus is not thought to be addictive. Its compounds have been used in the treatment of alcohol and morphine addiction.
 
===Dangerous interactions===
The main and absolute contraindication to using Blue Lotus, is the concurrent use of adrenergic receptor antagonists; combined, they cause a severe drop in blood pressure and fainting.
 
<small>L</small>-DOPA and Blue Lotus could pose risks and cause symptoms such as [[sleepiness]], [[dizziness]], [[Runny nose|runny nose]], [[sweating]] and [[Muscle twitching|tremors]].
{{DangerousInteractions/Intro}}
 
==Legal status==
''Nymphaea caerulea'' has been illegal in Latvia since November 2009. It is a schedule 1 drug. Possession of large quantities can be punished by up to 15 years in prison.
 
''Nymphaea caerulea'' was also banned in Poland in March 2009.
 
''Nymphaea caerulea'' has been illegal in [[Russia]] since April 2009.
 
''Nymphaea caerulea'' is completely prohibited in the state of Louisiana, making it the only state to ban the flower.
 
''Nymphaea caerulea,'' if sold for human consumption, could fall under the UK's ''Psychoactive Substances Act 2016,'' however, this law is rarely imposed on plants and small scale possession.
 
==See also==
 
*[[Responsible use]]
 
==External links==
(List along order below)
 
*[https://en.wikipedia.org/wiki/Nymphaea_nouchali_var._caerulea Blue Lotus (Wikipedia)]
*[https://www.erowid.org/plants/lotus/ Blue Lotus (Erowid Vault)]
 
==Literature==
 
*APA formatted reference
 
Please see the [[citation formatting guide]] if you need assistance properly formatting citations.
 
==References==
<references />
 
[[Category:Psychoactive substance]]
 
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Retrieved from "https://psy.st/wiki/Blue_Lotus"