This is an unofficial archive of PsychonautWiki as of 2025-08-08T03:33:20Z. Content on this page may be outdated, incomplete, or inaccurate. Please refer to the original page for the most up-to-date information.
Talk:Amisulpride: Difference between revisions
>Blackhole m fixed broken syntax |
>Blackhole m fixed link |
||
| (38 intermediate revisions by the same user not shown) | |||
| Line 9: | Line 9: | ||
==Chemistry== | ==Chemistry== | ||
{{chemistry}} | {{chemistry}} | ||
Amisulpride is the 4-position amino substitution of [[sulpiride]] which in turn is based on a [[chemical class::benzamide]] core. | |||
==Pharmacology== | ==Pharmacology== | ||
Amisulpride primarily works by antagonising D<sub>2</sub> and D<sub>3</sub> [[dopamine]] receptors aswell as the 5-HT<sub>7</sub>, 5-HT<sub>2A</sub> and 5-HT<sub>2B</sub> [[serotonin]] receptors. | |||
It is also known to act as a [[GHB receptor]] agonist and Mu- Delta- Kappa-[[opioid]] agonist<ref>Rehni AK, Singh TG, Chand P: Amisulpride-induced seizurogenic effect: a potential role of opioid receptor-linked transduction systems. Basic Clin Pharmacol Toxicol. 2011 May;108(5):310-7. doi: 10.1111/j.1742-7843.2010.00655.x. Epub 2010 Dec 22. (PubMed ID 21176108)</ref> | |||
==Subjective effects== | ==Subjective effects== | ||
| Line 32: | Line 36: | ||
*'''[[Effect::Thought deceleration]]''' | *'''[[Effect::Thought deceleration]]''' | ||
*'''[[Effect::Thought acceleration]]''' | *'''[[Effect::Thought acceleration]]''' contradictory side effect | ||
*'''[[Effect::Dream potentiation]]''' | *'''[[Effect::Dream potentiation]]''' | ||
| Line 54: | Line 58: | ||
==Legal status== | ==Legal status== | ||
{{LegalStub}} | {{LegalStub}} | ||
*'''Australia''': Amisulpride is a Schedule 4 prescription only drug.{{citation needed}} | |||
*'''Brazil''': Amisulpride is a Class C1 prescription only drug.<ref>https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-784-de-31-de-marco-de-2023-474904992</ref> | |||
*'''United Kingdom''': Amisulpride is a prescription only drug.<ref>https://web.archive.org/web/20200226225750/https://www.medicines.org.uk/emc/product/2726/smpc</ref> | |||
*'''United States''': Amisulpride is a prescription only drug.{{citation needed}} | |||
==See also== | ==See also== | ||
| Line 62: | Line 70: | ||
*[https://isomerdesign.com/PiHKAL/explore.php?id=9407 Amisulpride (Isomer Design)] | *[https://isomerdesign.com/PiHKAL/explore.php?id=9407 Amisulpride (Isomer Design)] | ||
*[https://go.drugbank.com/drugs/DB06288 Amisulpride (DrugBank)] | *[https://go.drugbank.com/drugs/DB06288 Amisulpride (DrugBank)] | ||
*[https://www.drugs.com/mtm/amisulpride.html#dosage Amisulpride (Drugs.com)] | |||
* | |||
==References== | ==References== | ||
| Line 74: | Line 78: | ||
[[Category:Antipsychotic]] | [[Category:Antipsychotic]] | ||
[[Category:Atypical Neuroleptic]] | [[Category:Atypical Neuroleptic]] | ||
[[Category:Opioid]] | |||
[[Category:Benzamide]] | |||
[[Category:Psychoactive substance]] | [[Category:Psychoactive substance]] | ||
[[Category:Proofread]] | [[Category:Proofread]] | ||
[[Category:Approval]] | [[Category:Approval]] | ||