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Talk:Estradiol: Difference between revisions
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{{SubstanceBox/Estradiol}} | {{SubstanceBox/Estradiol}} | ||
'''Estradiol''' (also known as | '''Estradiol''' (also known as '''oestradiol''', '''E''' or '''E2''') is an [[estrogen]] steroid hormone and the major female sex hormone. | ||
==History and culture== | ==History and culture== | ||
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==Chemistry== | ==Chemistry== | ||
===Esters=== | ===Esters=== | ||
As a medication '''estradiol''' is commonly(especially when injected) administered in the form of [[prodrug]] esters to improve duration of action. | |||
{| class="wikitable" | {| class="wikitable" | ||
|- | |- | ||
! scope="col" |'''Compound''' | ! scope="col" |'''Compound''' | ||
! scope="col" |'''Halflife via IM''' | |||
! scope="col" |'''Structure''' | ! scope="col" |'''Structure''' | ||
|- | |- | ||
|[[Estradiol Valerate]]||[[File:estradiol_valerate.svg|200px]] | |[[Estradiol Valerate]]||1.2–7.2 days||[[File:estradiol_valerate.svg|200px]] | ||
|- | |- | ||
|[[Estradiol Cypionate]]||[[File:estradiol_cypionate.svg|200px]] | |[[Estradiol Cypionate]]||8–10 days||[[File:estradiol_cypionate.svg|200px]] | ||
|- | |- | ||
|[[Estradiol Undecylate]]||[[File:estradiol_undecylate.svg|200px]] | |[[Estradiol Enantate]]||5.6–7.5 days||[[File:estradiol_enantate.svg|200px]] | ||
|- | |||
|[[Estradiol Undecylate]]||~1 month||[[File:estradiol_undecylate.svg|200px]] | |||
|- | |- | ||
|} | |} | ||
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==Subjective effects== | ==Subjective effects== | ||
{{Preamble/SubjectiveEffects}} | {{Preamble/SubjectiveEffects}} | ||
{{effects/base | |||
|{{effects/physical| | |||
'''Estradiol''' has feminzing develomental effects on the human body in regards of fat distribution, muscles mass and sexual characteristics. | |||
*'''[[Effect::Decreased libido]]''' | |||
*'''[[Effect::Orgasm depression]]''' | |||
*'''[[Effect::Body odor alteration]]''' | |||
*'''[[Effect::Body fat redistribution]]''' | |||
*'''[[Effect::Breast growth]]''' | |||
*'''[[Effect::Reduction of body hair]]''' | |||
*'''[[Effect::Softening of the skin]]''' | |||
}} | |||
|{{effects/cognitive| | |||
*'''[[Effect::Empathy, affection, and sociability enhancement]]''' | |||
*'''[[Effect::Cognitive euphoria]]''' Estradiol may directly produce feelings of euphoria in feminine people aswell as added euphoria due to gender affirming physical effects. | |||
*'''[[Effect::Cognitive dysphoria]]''' Estradiol might produce gender-dysphoria in masculine people | |||
}} | |||
{{effects/transpersonal| | |||
*'''[[Effect::Identity alteration]]''' | |||
}} | |||
}} | |||
===Experience reports=== | ===Experience reports=== | ||
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==External links== | ==External links== | ||
*[https://en.wikipedia.org/wiki/Estradiol Estradiol (Wikipedia)] | |||
* [https://en.wikipedia.org/wiki/Estradiol Estradiol (Wikipedia)] | *[https://go.drugbank.com/drugs/DB00783 Estradiol (DrugBank)] | ||
*[https://www.drugs.com/estradiol.html Estradiol (Drugs.com)] | |||
==References== | ==References== | ||