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Talk:Lamotrigine: Difference between revisions
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==Chemistry== | ==Chemistry== | ||
{{chemistry}} | {{chemistry}} | ||
Lamotrigine is a member of the sodium channel blocking class of antiepileptic drugs.[67] This may suppress the release of glutamate and aspartate, two dominant excitatory neurotransmitters in the central nervous system.[68] It is generally accepted to be a member of the sodium channel blocking class of antiepileptic drugs,[69] but it could have additional actions, since it has a broader spectrum of action than other sodium channel antiepileptic drugs such as phenytoin and is effective in the treatment of the depressed phase of bipolar disorder, whereas other sodium channel-blocking antiepileptic drugs are not, possibly on account of its sigma receptor activity. In addition, lamotrigine shares few side effects with other, unrelated anticonvulsants known to inhibit sodium channels, which further emphasizes its unique properties.[70] | |||
==Subjective effects== | ==Subjective effects== | ||
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You may select physical effects to add below [[Subjective effect index#Physical effects|here]]. | You may select physical effects to add below [[Subjective effect index#Physical effects|here]]. | ||
*'''[[Effect:: | *'''[[Effect::Sedation]]''' - Mild compared to benzodiazepines. | ||
*'''[[Effect:: | *'''[[Effect::Muscle relaxation]]''' | ||
*'''[[Effect:: | *'''[[Effect::Seizure suppression]]''' | ||
*'''[[Effect::Dehydration]]''' {{citation needed}} | |||
}} | |||
}} | }} | ||
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====Distortions==== | ====Distortions==== | ||
*'''[[Effect:: | *'''[[Effect::Drifting]]''' {{citation needed}} ''([[Drifting#Melting|melting]], [[Drifting#Flowing|flowing]], [[Drifting#Breathing|breathing]] and [[Drifting# morphing|morphing]])'' - This effect is relatively low compared to psychedelics. | ||
====[[Effect::Geometry]]==== | ====[[Effect::Geometry]]==== | ||
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You may select from a list of cognitive effects to add below [[Subjective effect index#Cognitive effects|here]]. | You may select from a list of cognitive effects to add below [[Subjective effect index#Cognitive effects|here]]. | ||
*'''[[Effect:: | *'''[[Effect::Mental stability increase]]''' | ||
*'''[[Effect::Dream potentiation]]''' {{citation needed}} | |||
*'''[[Effect::Cognitive effect2]]''' | *'''[[Effect::Cognitive effect2]]''' | ||
*'''[[Effect::Cognitive effect3]]''' | *'''[[Effect::Cognitive effect3]]''' | ||
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{{chemistry}} | {{chemistry}} | ||
==Pharmacology== | ==Pharmacology== | ||
Lamotrigine is a member of the sodium channel blocking class of antiepileptic drugs.This may suppress the release of glutamate and aspartate, two dominant excitatory neurotransmitters in the central nervous system.It is generally accepted to be a member of the sodium channel blocking class of antiepileptic drugs, but it could have additional actions, since it has a broader spectrum of action than other sodium channel antiepileptic drugs such as phenytoin and is effective in the treatment of the depressed phase of bipolar disorder, whereas other sodium channel-blocking antiepileptic drugs are not, possibly on account of its sigma receptor activity. In addition, lamotrigine shares few side effects with other, unrelated anticonvulsants known to inhibit sodium channels, which further emphasizes its unique properties. | |||
==Subjective effects== | ==Subjective effects== | ||