PsychonautWiki Archive

Talk:Phenylephrine: Difference between revisions

← Older edit
>Xbdab
Updated
>SquaricAcid
m phenylephrine has no psychedelic action and is definitely not a tryptamine (fixed this)
 
(13 intermediate revisions by 2 users not shown)
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     <!-- Structure -->
     <!-- Structure -->
     |MolecularStructureCaption=
     |MolecularStructureCaption=
     |SkeletalImageFile=File:DMT.svg
     |SkeletalImageFile=File:Phenylephrine_Structural_Formula_V1.svg
    |SkeletalImageWidth=245px
     |3DImageFile=
     |3DImageFile=
     |3DImageWidth=
     |3DImageWidth=


     <!-- Nomenclature -->
     <!-- Nomenclature -->
     |NameCommon=DMT, Dimethyltryptamine, Dmitri
     |NameCommon=Phenylephrine
     |NameSubstitution=N,N-Dimethyltryptamine
     |NameSubstitution=Neo-synephrine, m-Synephrine, β-HO-N-Me-3-HPEA
     |NameSystematic=2-(1H-Indol-3-yl)-N,N-dimethylethanamine <!-- Use IUPAC naming convention -->
     |NameSystematic=3-[1-Hydroxy-2-(methylamino)ethyl]phenol


     <!-- Class Membership -->
     <!-- Class Membership -->
     |EffectClass=[[psychoactive class::Psychedelic]]
     |EffectClass=[[psychoactive class::Stimulant]]
     |ChemicalClass=[[chemical class::Tryptamine]]
     |ChemicalClass=[[chemical class::Phenethylamine]]


     <!-- Dosage/Duration per ROA -->
     <!-- Dosage/Duration per ROA -->


     |OralROA=true
     |OralROA=true
     |OralROA_Collapsed=false
     |OralROA_Collapsed=true
     |OralROA_Caption=
     |OralROA_Caption=
     |OralROA_Bioavailability=[[Oral min bioavailability::x]]% - [[Oral max bioavailability::y]]%<ref>APA formatted citation.</ref> <!-- Refer to this tool to generate APA citations from DOI links: https://reftag.appspot.com/doiweb.py -->
     |OralROA_Bioavailability=[[Oral min bioavailability::38]]% - [[Oral max bioavailability::38]]%
     |OralROA_Microdose=
     |OralROA_Microdose=
     |OralROA_Threshold=[[Oral threshold dose::x]] -  [[Oral dose units::mg]]  
     |OralROA_Threshold=[[Oral threshold dose::3]] -  [[Oral dose units::mg]]  
     |OralROA_Light=[[Oral min light dose::x]] - [[Oral max light dose::y]] mg
     |OralROA_Light=[[Oral min light dose::5]] - [[Oral max light dose::9]] mg
     |OralROA_Common=[[Oral min common dose::x]] - [[Oral max common dose::y]] mg
     |OralROA_Common=[[Oral min common dose::10]] - [[Oral max common dose::y]] mg
     |OralROA_Strong=[[Oral min strong dose::x]] - [[Oral max strong dose::y]] mg
     |OralROA_Strong=[[Oral min strong dose::x]] - [[Oral max strong dose::59]] mg
     |OralROA_Heavy=[[Oral heavy dose::x]] mg +
     |OralROA_Heavy=[[Oral heavy dose::60]] mg +
     |OralROA_TimelineFile=
     |OralROA_TimelineFile=
     |OralROA_TimelineWidth=
     |OralROA_TimelineWidth=
     |OralROA_Duration=[[Oral min total time::x]] - [[Oral max total time::y]] [[Oral total time units::hours]]
     |OralROA_Duration=[[Oral min total time::4]] - [[Oral max total time::4]] [[Oral total time units::hours]]
     |OralROA_Onset=[[Oral min onset time::x]] - [[Oral max onset time::y]] [[Oral onset time units::minutes]]
     |OralROA_Onset=[[Oral min onset time::20]] - [[Oral max onset time::20]] [[Oral onset time units::minutes]]
     |OralROA_Comeup=[[Oral min comeup time::x]] - [[Oral max comeup time::y]] [[Oral comeup time units::minutes]]
     |OralROA_Comeup=[[Oral min comeup time::x]] - [[Oral max comeup time::y]] [[Oral comeup time units::minutes]]
     |OralROA_Peak=[[Oral min peak time::x]] - [[Oral max peak time::y]] [[Oral peak time units::hours]]
     |OralROA_Peak=[[Oral min peak time::x]] - [[Oral max peak time::y]] [[Oral peak time units::hours]]
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     |OralROA_Aftereffects=[[Oral min afterglow time::x]] - [[Oral max afterglow time::y]] [[Oral afterglow time units::hours]]
     |OralROA_Aftereffects=[[Oral min afterglow time::x]] - [[Oral max afterglow time::y]] [[Oral afterglow time units::hours]]


     |SublingualROA=true
     |InsufflatedROA=true
     |SublingualROA_Collapsed=true
     |InsufflatedROA_Collapsed=false
    |SublingualROA_Caption=
    |SublingualROA_Bioavailability=[[Sublingual min bioavailability::x]]% - [[Sublingual max bioavailability::y]]%
    |SublingualROA_Microdose=
    |SublingualROA_Threshold=[[Sublingual threshold dose::x]] - [[Sublingual dose units::mg]]
    |SublingualROA_Light=[[Sublingual min light dose::x]] - [[Sublingual max light dose::y]] mg
    |SublingualROA_Common=[[Sublingual min common dose::x]] - [[Sublingual max common dose::y]] mg
    |SublingualROA_Strong=[[Sublingual min strong dose::x]] - [[Sublingual max strong dose::y]] mg
    |SublingualROA_Heavy=[[Sublingual heavy dose::x]] mg +
    |SublingualROA_TimelineFile=
    |SublingualROA_TimelineWidth=
    |SublingualROA_Duration=[[Sublingual min total time::a]] - [[Sublingual max total time::b]] [[Sublingual total time units::hours]]
    |SublingualROA_Onset=[[Sublingual min onset time::a]] - [[Sublingual max onset time::b]] [[Sublingual onset time units::minutes]]
    |SublingualROA_Comeup=[[Sublingual min comeup time::a]] - [[Sublingual max comeup time::b]] [[Sublingual comeup time units::minutes]]
    |SublingualROA_Peak=[[Sublingual min peak time::a]] - [[Sublingual max peak time::b]] [[Sublingual peak time units::hours]]
    |SublingualROA_Offset=[[Sublingual min offset time::a]] - [[Sublingual max offset time::b]] [[Sublingual offset time units::hours]]
    |SublingualROA_Aftereffects=[[Sublingual min afterglow time::a]] - [[Sublingual max afterglow time::b]] [[Sublingual afterglow time units::hours]]
 
    |BuccalROA=false
    |BuccalROA_Collapsed=True
    |BuccalROA_Caption=
    |BuccalROA_Bioavailability=[[Buccal min bioavailability::x]]% - [[Buccal max bioavailability::y]]%<ref>APA formatted citation</ref>
    |BuccalROA_Microdose=
    |BuccalROA_Threshold=[[Buccal threshold dose::x]] -  [[Buccal dose units::mg]]
    |BuccalROA_Light=[[Buccal min light dose::x]] - [[Buccal max light dose::y]] mg
    |BuccalROA_Common=[[Buccal min common dose::x]] - [[Buccal max common dose::y]] mg
    |BuccalROA_Strong=[[Buccal min strong dose::x]] - [[Buccal max strong dose::y]] mg
    |BuccalROA_Heavy=[[Buccal heavy dose::x]] mg +
    |BuccalROA_TimelineFile=
    |BuccalROA_TimelineWidth=
    |BuccalROA_Duration=[[Buccal min total time::x]] - [[Buccal max total time::y]] [[Buccal total time units::hours]]
    |BuccalROA_Onset=[[Buccal min onset time::x]] - [[Buccal max onset time::y]] [[Buccal onset time units::minutes]]
    |BuccalROA_Comeup=[[Buccal min comeup time::x]] - [[Buccal max comeup time::y]] [[Buccal comeup time units::minutes]]
    |BuccalROA_Peak=[[Buccal min peak time::x]] - [[Buccal max peak time::y]] [[Buccal peak time units::hours]]
    |BuccalROA_Offset=[[Buccal min offset time::x]] - [[Buccal max offset time::y]] [[Buccal offset time units::hours]]
    |BuccalROA_Aftereffects=[[Buccal min afterglow time::x]] - [[Buccal max afterglow time::y]] [[Buccal afterglow time units::hours]]
 
    |InsufflatedROA=false
    |InsufflatedROA_Collapsed=True
     |InsufflatedROA_Caption=
     |InsufflatedROA_Caption=
     |InsufflatedROA_Bioavailability=[[Insufflated min bioavailability::x]]% - [[Insufflated max bioavailability::y]]%<ref>APA formatted citation</ref>
     |InsufflatedROA_Bioavailability=
     |InsufflatedROA_Microdose=
     |InsufflatedROA_Microdose=
     |InsufflatedROA_Threshold=[[Insufflated threshold dose::x]] -  [[Insufflated dose units::mg]]  
     |InsufflatedROA_Threshold=[[Insufflated threshold dose::x]] -  [[Insufflated dose units::mg]]  
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     |InsufflatedROA_Offset=[[Insufflated min offset time::x]] - [[Insufflated max offset time::y]] [[Insufflated offset time units::hours]]
     |InsufflatedROA_Offset=[[Insufflated min offset time::x]] - [[Insufflated max offset time::y]] [[Insufflated offset time units::hours]]
     |InsufflatedROA_Aftereffects=[[Insufflated min afterglow time::x]] - [[Insufflated max afterglow time::y]] [[Insufflated afterglow time units::hours]]
     |InsufflatedROA_Aftereffects=[[Insufflated min afterglow time::x]] - [[Insufflated max afterglow time::y]] [[Insufflated afterglow time units::hours]]
    |RectalROA=false
    |RectalROA_Collapsed=True
    |RectalROA_Caption=
    |RectalROA_Bioavailability=[[Rectal min bioavailability::x]]% - [[Rectal max bioavailability::y]]
    |RectalROA_Microdose=
    |RectalROA_Threshold=[[Rectal threshold dose::x]] -  [[Rectal dose units::mg]]
    |RectalROA_Light=[[Rectal min light dose::x]] - [[Rectal max light dose::y]] mg
    |RectalROA_Common=[[Rectal min common dose::x]] - [[Rectal max common dose::y]] mg
    |RectalROA_Strong=[[Rectal min strong dose::x]] - [[Rectal max strong dose::y]] mg
    |RectalROA_Heavy=[[Rectal heavy dose::x]] mg +
    |RectalROA_TimelineFile=
    |RectalROA_TimelineWidth=
    |RectalROA_Duration=[[Rectal min total time::x]] - [[Rectal max total time::y]] [[Rectal total time units::hours]]
    |RectalROA_Onset=[[Rectal min onset time::x]] - [[Rectal max onset time::y]] [[Rectal onset time units::minutes]]
    |RectalROA_Comeup=[[Rectal min comeup time::x]] - [[Rectal max comeup time::y]] [[Rectal comeup time units::minutes]]
    |RectalROA_Peak=[[Rectal min peak time::x]] - [[Rectal max peak time::y]] [[Rectal peak time units::hours]]
    |RectalROA_Offset=[[Rectal min offset time::x]] - [[Rectal max offset time::y]] [[Rectal offset time units::hours]]
    |RectalROA_Aftereffects=[[Rectal min afterglow time::x]] - [[Rectal max afterglow time::y]] [[Rectal afterglow time units::hours]]
    |TransdermalROA=false
    |TransdermalROA_Collapsed=True
    |TransdermalROA_Caption=
    |TransdermalROA_Bioavailability=[[Transdermal min bioavailability::x]]% - [[Transdermal max bioavailability::y]]%<ref>APA formatted citation</ref>
    |TransdermalROA_Microdose=
    |TransdermalROA_Threshold=[[Transdermal threshold dose::x]] -  [[Transdermal dose units::mg]]
    |TransdermalROA_Light=[[Transdermal min light dose::x]] - [[Transdermal max light dose::y]] mg
    |TransdermalROA_Common=[[Transdermal min common dose::x]] - [[Transdermal max common dose::y]] mg
    |TransdermalROA_Strong=[[Transdermal min strong dose::x]] - [[Transdermal max strong dose::y]] mg
    |TransdermalROA_Heavy=[[Transdermal heavy dose::x]] mg +
    |TransdermalROA_TimelineFile=
    |TransdermalROA_TimelineWidth=
    |TransdermalROA_Duration=[[Transdermal min total time::x]] - [[Transdermal max total time::y]] [[Transdermal total time units::hours]]
    |TransdermalROA_Onset=[[Transdermal min onset time::x]] - [[Transdermal max onset time::y]] [[Transdermal onset time units::minutes]]
    |TransdermalROA_Comeup=[[Transdermal min comeup time::x]] - [[Transdermal max comeup time::y]] [[Transdermal comeup time units::minutes]]
    |TransdermalROA_Peak=[[Transdermal min peak time::x]] - [[Transdermal max peak time::y]] [[Transdermal peak time units::hours]]
    |TransdermalROA_Offset=[[Transdermal min offset time::x]] - [[Transdermal max offset time::y]] [[Transdermal offset time units::hours]]
    |TransdermalROA_Aftereffects=[[Transdermal min afterglow time::x]] - [[Transdermal max afterglow time::y]] [[Transdermal afterglow time units::hours]]
    |SubcutaneousROA=false
    |SubcutaneousROA_Collapsed=True
    |SubcutaneousROA_Caption=
    |SubcutaneousROA_Bioavailability=[[Subcutaneous min bioavailability::x]]% - [[Subcutaneous max bioavailability::y]]%<ref>APA formatted citation</ref>
    |SubcutaneousROA_Microdose=
    |SubcutaneousROA_Threshold=[[Subcutaneous threshold dose::x]] -  [[Subcutaneous dose units::mg]]
    |SubcutaneousROA_Light=[[Subcutaneous min light dose::x]] - [[Subcutaneous max light dose::y]] mg
    |SubcutaneousROA_Common=[[Subcutaneous min common dose::x]] - [[Subcutaneous max common dose::y]] mg
    |SubcutaneousROA_Strong=[[Subcutaneous min strong dose::x]] - [[Subcutaneous max strong dose::y]] mg
    |SubcutaneousROA_Heavy=[[Subcutaneous heavy dose::x]] mg +
    |SubcutaneousROA_TimelineFile=
    |SubcutaneousROA_TimelineWidth=
    |SubcutaneousROA_Duration=[[Subcutaneous min total time::x]] - [[Subcutaneous max total time::y]] [[Subcutaneous total time units::hours]]
    |SubcutaneousROA_Onset=[[Subcutaneous min onset time::x]] - [[Subcutaneous max onset time::y]] [[Subcutaneous onset time units::minutes]]
    |SubcutaneousROA_Comeup=[[Subcutaneous min comeup time::x]] - [[Subcutaneous max comeup time::y]] [[Subcutaneous comeup time units::minutes]]
    |SubcutaneousROA_Peak=[[Subcutaneous min peak time::x]] - [[Subcutaneous max peak time::y]] [[Subcutaneous peak time units::hours]]
    |SubcutaneousROA_Offset=[[Subcutaneous min offset time::x]] - [[Subcutaneous max offset time::y]] [[Subcutaneous offset time units::hours]]
    |SubcutaneousROA_Aftereffects=[[Subcutaneous min afterglow time::x]] - [[Subcutaneous max afterglow time::y]] [[Subcutaneous afterglow time units::hours]]
    |IntramuscularROA=false
    |IntramuscularROA_Collapsed=true
    |IntramuscularROA_Caption=
    |IntramuscularROA_Bioavailability=[[Intramuscular min bioavailability::x]]% - [[Intramuscular max bioavailability::y]]%<ref>APA formatted citation</ref>
    |IntramuscularROA_Microdose=
    |IntramuscularROA_Threshold=[[Intramuscular threshold dose::x]] -  [[Intramuscular dose units::mg]]
    |IntramuscularROA_Light=[[Intramuscular min light dose::x]] - [[Intramuscular max light dose::y]] mg
    |IntramuscularROA_Common=[[Intramuscular min common dose::x]] - [[Intramuscular max common dose::y]] mg
    |IntramuscularROA_Strong=[[Intramuscular min strong dose::x]] - [[Intramuscular max strong dose::y]] mg
    |IntramuscularROA_Heavy=[[Intramuscular heavy dose::x]] mg +
    |IntramuscularROA_TimelineFile=
    |IntramuscularROA_TimelineWidth=
    |IntramuscularROA_Duration=[[Intramuscular min total time::x]] - [[Intramuscular max total time::y]] [[Intramuscular total time units::hours]]
    |IntramuscularROA_Onset=[[Intramuscular min onset time::x]] - [[Intramuscular max onset time::y]] [[Intramuscular onset time units::minutes]]
    |IntramuscularROA_Comeup=[[Intramuscular min comeup time::x]] - [[Intramuscular max comeup time::y]] [[Intramuscular comeup time units::minutes]]
    |IntramuscularROA_Peak=[[Intramuscular min peak time::x]] - [[Intramuscular max peak time::y]] [[Intramuscular peak time units::hours]]
    |IntramuscularROA_Offset=[[Intramuscular min offset time::x]] - [[Intramuscular max offset time::y]] [[Intramuscular offset time units::hours]]
    |IntramuscularROA_Aftereffects=[[Intramuscular min afterglow time::x]] - [[Intramuscular max afterglow time::y]] [[Intramuscular afterglow time units::hours]]
    |IntravenousROA=false
    |IntravenousROA_Collapsed=true
    |IntravenousROA_Caption=
    |IntravenousROA_Bioavailability=[[Intravenous min bioavailability::x]]% - [[Intravenous max bioavailability::y]]%<ref>APA formatted citation</ref>
    |IntravenousROA_Microdose=
    |IntravenousROA_Threshold=[[Intravenous threshold dose::x]] -  [[Intravenous dose units::mg]]
    |IntravenousROA_Light=[[Intravenous min light dose::x]] - [[Intravenous max light dose::y]] mg
    |IntravenousROA_Common=[[Intravenous min common dose::x]] - [[Intravenous max common dose::y]] mg
    |IntravenousROA_Strong=[[Intravenous min strong dose::x]] - [[Intravenous max strong dose::y]] mg
    |IntravenousROA_Heavy=[[Intravenous heavy dose::x]] mg +
    |IntravenousROA_TimelineFile=
    |IntravenousROA_TimelineWidth=
    |IntravenousROA_Duration=[[Intravenous min total time::x]] - [[Intravenous max total time::y]] [[Intravenous total time units::hours]]
    |IntravenousROA_Onset=[[Intravenous min onset time::x]] - [[Intravenous max onset time::y]] [[Intravenous onset time units::minutes]]
    |IntravenousROA_Comeup=[[Intravenous min comeup time::x]] - [[Intravenous max comeup time::y]] [[Intravenous comeup time units::minutes]]
    |IntravenousROA_Peak=[[Intravenous min peak time::x]] - [[Intravenous max peak time::y]] [[Intravenous peak time units::hours]]
    |IntravenousROA_Offset=[[Intravenous min offset time::x]] - [[Intravenous max offset time::y]] [[Intravenous offset time units::hours]]
    |IntravenousROA_Aftereffects=[[Intravenous min afterglow time::x]] - [[Intravenous max afterglow time::y]] [[Intravenous afterglow time units::hours]]


}}
}}
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Phenylephrine was patented in 1927 and came into medical use in 1938. It is available as a generic medication
Phenylephrine was patented in 1927 and came into medical use in 1938. It is available as a generic medication


==Chemistry==
{{chemistry}}
==Pharmacology==
==Pharmacology==
{{pharmacology}}
{{pharmacology}}
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==Subjective effects==
==Subjective effects==
{{EffectStub}}
{{Preamble/SubjectiveEffects}}
{{Preamble/SubjectiveEffects}}
{{effects/base
{{effects/base
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|{{effects/physical|
|{{effects/physical|


*'''[[Nasal decongestion]]'''
*'''[[Effect::Pupil dilation]]''' - Most common when used in eye drops  
*'''[[Effect::Pupil dilation]]''' - Most common when used in eye drops  
*'''[[Effect::Increased blood pressure]]'''
*'''[[Effect::Increased blood pressure]]'''
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* [https://en.wikipedia.org/wiki/Phenylephrine Phenylephrine (Wikipedia)]
* [https://en.wikipedia.org/wiki/Phenylephrine Phenylephrine (Wikipedia)]
* [https://www.erowid.org/experiences/subs/exp_Pharms_Phenylephrine.shtml Phenylephrine (Erowid Vault)]
* [https://www.erowid.org/experiences/subs/exp_Pharms_Phenylephrine.shtml Phenylephrine (Erowid Vault)]
* [https://isomerdesign.com/PiHKAL/explore.php?id=6157&name=Phenylephrine Phenylephrine (Isomer Design)]
* [https://www.drugs.com/mtm/phenylephrine.html Phenylephrine (Drugs.com)]
* [https://www.drugs.com/mtm/phenylephrine.html Phenylephrine (Drugs.com)]
* [https://pubchem.ncbi.nlm.nih.gov/compound/6041 Phenylephrine (Pubchem)]  
* [https://pubchem.ncbi.nlm.nih.gov/compound/6041 Phenylephrine (Pubchem)]  
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