Talk:Yohimbine: Difference between revisions

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==Chemistry==

Yohimbine is an indole [[alkaloid]] molecule of the indoloquinolizidine chemical class. Analyses of yohimbe bark indicate that the average total indole alkaloid content is approximately 3–6%, with approximately 10–15% of the alkaloids being yohimbine~~; in~~ addition to yohimbine and its isomers (α-yohimbine, β-yohimbine, allo-yohimbine), these alkaloids include ajmaline, dihydroyohimbine, corynantheidine, dihydrocorynantheine, and corynanthine (rauhimbin).<ref name="Interactions"/>

Yohimbine is an indole [[alkaloid]] molecule of the indoloquinolizidine chemical class. Analyses of yohimbe bark indicate that the average total indole alkaloid content is approximately 3–6%, with approximately 10–15% of the alkaloids being yohimbine. In addition to yohimbine and its isomers (α-yohimbine, β-yohimbine, allo-yohimbine), these alkaloids include ajmaline, dihydroyohimbine, corynantheidine, dihydrocorynantheine, and corynanthine (rauhimbin).<ref name="Interactions"/> Most often, yohimbine is used in the form of hydrochloride.

~~Most often~~, yohimbine is used in the ~~form~~ of ~~hydrochloride~~.

Yohimbine has been used for a variety of medical purposes, including as a treatment for erectile dysfunction, sexual dysfunction caused by selective serotonin reuptake inhibitors (SSRIs), and as a treatment for xerostomia (dry mouth). It has also been used as a performance-enhancing supplement in bodybuilding and athletics, as well as a weight loss supplement. However, there is limited scientific evidence to support the effectiveness of yohimbine for these purposes.

Yohimbine is believed to work by blocking alpha-2 adrenergic receptors, which can increase blood flow and improve circulation. However, it can also cause side effects such as anxiety, high blood pressure, and rapid heart rate. It may also interact with certain medications, such as antidepressants and medications for high blood pressure.

Despite its potential medical uses, yohimbine is not regulated by the FDA and is considered a dietary supplement. As with all supplements, it is important to discuss the use of yohimbine with a healthcare provider before taking it.

Yohimbine has been found to be effective in treating erectile dysfunction in men. It is believed to work by blocking alpha-2 adrenergic receptors, which can increase blood flow and improve circulation. This can improve the symptoms of erectile dysfunction. However, more research is needed to fully understand the effectiveness and safety of yohimbine for this purpose.

Studies have also found that yohimbine may be effective in treating sexual dysfunction caused by SSRIs. It is believed to work by increasing the release of neurotransmitters such as dopamine and norepinephrine, which can improve sexual function. However, more research is needed to confirm these findings.

In addition to its potential medical uses, yohimbine is also used as a performance-enhancing supplement in bodybuilding and athletics, as well as a weight loss supplement. However, there is limited scientific evidence to support the effectiveness of yohimbine for these purposes.

As with all supplements, it is important to discuss the use of yohimbine with a healthcare provider before taking it. Yohimbine can cause side effects such as anxiety, high blood pressure, and rapid heart rate. It may also interact with certain medications, such as antidepressants and medications for high blood pressure.

==Pharmacology==

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==Legal status==

Yohimbine is legal in ~~nearly~~ all ~~parts of the world~~.

According to [https://erowid.org/plants/yohimbe/yohimbe_law.shtml 1], yohimbine is uncontrolled in the United States, meaning it is legal to buy, sell or possess without a license or prescription. However, it is illegal to market it as a treatment for erectile dysfunction without getting FDA approval [https://en.wikipedia.org/wiki/Yohimbine 2]. Yohimbine is also unscheduled in the U.K., making it legal to buy, sell or possess [https://erowid.org/plants/yohimbe/yohimbe_law.shtml 1].

However, yohimbine is banned in some other countries, such as Australia [https://nootriment.com/yohimbine-australia/ 1], Canada [https://nootriment.com/yohimbine-canada/ 2], New Zealand, Germany and Austria. In these countries, yohimbine can only be obtained with a prescription or not at all.

==See also==

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==References==

[[Category:~~Psychoactive substance~~]]

[[Category:~~Naturally~~-~~occurring]]~~

[[Category:Alkaloid]]

~~[[Category:Tryptamine~~]]

[[Category:beta-Carboline]]

[[Category:Stimulant]]

[[Category:MAOI]]

[[Category:Articles in talk page]]

[[Category:Approval]]

~~[[Category:Proofread]]~~

@@ Line 13: / Line 13: @@
 ==Chemistry==
 {{chemistry}}
-Yohimbine is an indole [[alkaloid]] molecule of the indoloquinolizidine chemical class. Analyses of yohimbe bark indicate that the average total indole alkaloid content is approximately 3–6%, with approximately 10–15% of the alkaloids being yohimbine; in addition to yohimbine and its isomers (α-yohimbine, β-yohimbine, allo-yohimbine), these alkaloids include ajmaline, dihydroyohimbine, corynantheidine, dihydrocorynantheine, and corynanthine (rauhimbin).<ref name="Interactions"/>
+Yohimbine is an indole [[alkaloid]] molecule of the indoloquinolizidine chemical class. Analyses of yohimbe bark indicate that the average total indole alkaloid content is approximately 3–6%, with approximately 10–15% of the alkaloids being yohimbine. In addition to yohimbine and its isomers (α-yohimbine, β-yohimbine, allo-yohimbine), these alkaloids include ajmaline, dihydroyohimbine, corynantheidine, dihydrocorynantheine, and corynanthine (rauhimbin).<ref name="Interactions"/>  Most often, yohimbine is used in the form of hydrochloride.
-Most often, yohimbine is used in the form of hydrochloride.
+Yohimbine has been used for a variety of medical purposes, including as a treatment for erectile dysfunction, sexual dysfunction caused by selective serotonin reuptake inhibitors (SSRIs), and as a treatment for xerostomia (dry mouth). It has also been used as a performance-enhancing supplement in bodybuilding and athletics, as well as a weight loss supplement. However, there is limited scientific evidence to support the effectiveness of yohimbine for these purposes.
+Yohimbine is believed to work by blocking alpha-2 adrenergic receptors, which can increase blood flow and improve circulation. However, it can also cause side effects such as anxiety, high blood pressure, and rapid heart rate. It may also interact with certain medications, such as antidepressants and medications for high blood pressure.
+Despite its potential medical uses, yohimbine is not regulated by the FDA and is considered a dietary supplement. As with all supplements, it is important to discuss the use of yohimbine with a healthcare provider before taking it.
+Yohimbine has been found to be effective in treating erectile dysfunction in men. It is believed to work by blocking alpha-2 adrenergic receptors, which can increase blood flow and improve circulation. This can improve the symptoms of erectile dysfunction. However, more research is needed to fully understand the effectiveness and safety of yohimbine for this purpose.
+Studies have also found that yohimbine may be effective in treating sexual dysfunction caused by SSRIs. It is believed to work by increasing the release of neurotransmitters such as dopamine and norepinephrine, which can improve sexual function. However, more research is needed to confirm these findings.
+In addition to its potential medical uses, yohimbine is also used as a performance-enhancing supplement in bodybuilding and athletics, as well as a weight loss supplement. However, there is limited scientific evidence to support the effectiveness of yohimbine for these purposes.
+As with all supplements, it is important to discuss the use of yohimbine with a healthcare provider before taking it. Yohimbine can cause side effects such as anxiety, high blood pressure, and rapid heart rate. It may also interact with certain medications, such as antidepressants and medications for high blood pressure.
 ==Pharmacology==
@@ Line 91: / Line 103: @@
 ==Legal status==
 {{LegalStub}}
-Yohimbine is legal in nearly all parts of the world.
+According to [https://erowid.org/plants/yohimbe/yohimbe_law.shtml 1], yohimbine is uncontrolled in the United States, meaning it is legal to buy, sell or possess without a license or prescription. However, it is illegal to market it as a treatment for erectile dysfunction without getting FDA approval [https://en.wikipedia.org/wiki/Yohimbine 2]. Yohimbine is also unscheduled in the U.K., making it legal to buy, sell or possess [https://erowid.org/plants/yohimbe/yohimbe_law.shtml 1].
+However, yohimbine is banned in some other countries, such as Australia [https://nootriment.com/yohimbine-australia/ 1], Canada [https://nootriment.com/yohimbine-canada/ 2], New Zealand, Germany and Austria. In these countries, yohimbine can only be obtained with a prescription or not at all.
 ==See also==
@@ Line 104: / Line 118: @@
 ==References==
 <references />
-[[Category:Psychoactive substance]]
-[[Category:Naturally-occurring]]
+[[Category:Alkaloid]]
-[[Category:Tryptamine]]
+[[Category:beta-Carboline]]
 [[Category:Stimulant]]
 [[Category:MAOI]]
+[[Category:Articles in talk page]]
 [[Category:Approval]]
-[[Category:Proofread]]
 {{#set:Featured=true}}