Category:Lysergamide: Difference between revisions

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~~[[File:Lysergamide.png~~|~~thumb|right|261px|General formula of ergoline derivative.]]~~

[[Category:Base Structures]]

~~Amides of '''lysergic acid''' are collectively known as ''~~Lysergamides~~''.~~

[[Category:Phenethylamine]]

[[Category:Tryptamine]]

~~''Ergoline'' refers to a class of compounds derived from alkaloids of a group of fungi known as '''Ergot''', in the ''Claviceps'' genus. These compounds typically have have strong psychedelic effects.~~

~~==Chemistry==~~

~~Lysergamides, tabulated by structure (~~[[~~wikipedia~~:~~Lysergamides|Wikipedia~~]])

~~{| border=1~~

~~!Name !! R1 !! R6 !! R2 !! R3~~

|-

| [[~~Lysergic acid amide|LSA]] / [[Lysergic acid amide|LAA~~]] ~~|| H || [[Methyl|CH3]] || H || H~~

|-

| [[~~DAM-57]] || H || CH3 || CH3 || CH3~~

|-

~~| [[Ergometrine]] (Ergonovine) || H || CH3 || CH(CH3)CH2OH || H~~

|-

~~| [[Ergotamine]] || H || CH3 || -- || C17H18N2O4~~

|-

~~| [[Methergine]] || H || CH3 || CH(CH2CH3)CH2OH || H~~

|-

~~| [[Methysergide]] || CH3 || CH3 || CH(CH2CH3)CH2OH || H~~

|-

~~| [[LAE-32]] || H || CH3 || [[Ethyl group|CH2CH3]] || H~~

|-

~~| [[Lysergic acid 2-butyl amide|LSB]] || H || CH3 || CH(CH3)CH2CH3 || H~~

|-

~~| [[Lysergic acid 3-pentyl amide|LSP~~]] ~~|| H || CH3 || CH(CH2CH3)CH2CH3 || H~~

|-

~~| [[Diallyllysergamide|DAL]] || H || CH3 || [[Allyl|H2C=CH-CH2]] || Allyl|H2C=CH-CH2~~

|-

~~| [[Methylisopropyllysergamide|MIPLA]] || H || CH3 || [[Isopropyl|CH(CH3)2]] || CH3~~

|-

~~| [[Ethylisopropyllysergamide|EIPLA]] || H || CH3 || CH(CH3)2 || CH2CH3~~

|-

~~| [[Methylpropyllysergamide|LAMP]] || H || CH3 || CH2CH2CH3 || CH3~~

|-

~~| '''[[LSD]]''' / [[LSD|LAD]] || H || CH3 || CH2CH3 || CH2CH3~~

|-

~~| [[ETH-LAD]] || H || CH2CH3 || CH2CH3 || CH2CH3~~

|-

~~| [[PARGY-LAD]] || H || [[Propynyl|HC≡C−CH2]] || CH2CH3 || CH2CH3~~

|-

~~| [[AL-LAD]] || H || H2C=CH-CH2 || CH2CH3 || CH2CH3~~

|-

~~| [[PRO-LAD]] || H || [[Propyl|CH2CH2CH3]] || CH2CH3 || CH2CH3~~

|-

~~| [[CYP-LAD]] || H || [[Cyclopropyl|C3H5]] || CH2CH3 || CH2CH3~~

|-

~~| [[BU-LAD]] || H || [[Butyl|CH2CH2CH2CH3]] || CH2CH3 || CH2CH3~~

|-

~~| [[ALD-52]] || [[Acetyl|COCH3]] || CH3 || CH2CH3 || CH2CH3~~

|-

~~| [[MLD-41]] || CH3 || CH3 || CH2CH3 || CH2CH3~~

|-

~~| [[LSM-775]] || H || CH3 || colspan=2|[[Morpholine|CH2CH2-O-CH2CH2]]~~

|-

~~| [[LPD-824]] || H || CH3 || colspan=2|[[Pyrrolidine|CH2CH2~~

~~CH2CH2]]~~

|-

~~| [[LSD-Pip]] || H || CH3 || colspan=2|[[Piperidine|CH2CH2~~

~~CH2CH2CH2]]~~

|-

~~| [[Lysergic acid 2,4-dimethylazetidide|LA-SS-Az]] || H || CH3 || colspan=2|CH2(CHCH3)2CH2~~

|}

~~==Pharmacology==~~

~~Lysergamides are believed to produce their psychedelic effect primarily by partial agonism of [[Serotonin#The 5-HT System|5-HT2A receptors]].~~

[[Category:Psychedelic]]

@@ Line 1: / Line 1: @@
-[[File:Lysergamide.png|thumb|right|261px|General formula of ergoline derivative.]]
+{{Page|Lysergamides}}
+[[Category:Base Structures]]
-Amides of '''lysergic acid''' are collectively known as ''Lysergamides''.
+[[Category:Phenethylamine]]
+[[Category:Tryptamine]]
-''Ergoline'' refers to a class of compounds derived from alkaloids of a group of fungi known as '''Ergot''', in the ''Claviceps'' genus. These compounds typically have have strong psychedelic effects.
-==Chemistry==
-Lysergamides, tabulated by structure ([[wikipedia:Lysergamides|Wikipedia]])
-{| border=1
-!Name !! R1 !! R6 !! R2 !! R3
-|-
-| [[Lysergic acid amide|LSA]] / [[Lysergic acid amide|LAA]] || H || [[Methyl|CH<sub>3</sub>]] || H || H
-|-
-| [[DAM-57]] || H || CH<sub>3</sub> || CH<sub>3</sub> || CH<sub>3</sub>
-|-
-| [[Ergometrine]] (Ergonovine) || H || CH<sub>3</sub> || CH(CH<sub>3</sub>)CH<sub>2</sub>OH || H
-|-
-| [[Ergotamine]] || H || CH<sub>3</sub> || -- || C<sub>17</sub>H<sub>18</sub>N<sub>2</sub>O<sub>4</sub>
-|-
-| [[Methergine]] || H || CH<sub>3</sub> || CH(CH<sub>2</sub>CH<sub>3</sub>)CH<sub>2</sub>OH || H
-|-
-| [[Methysergide]] || CH<sub>3</sub> ||  CH<sub>3</sub> || CH(CH<sub>2</sub>CH<sub>3</sub>)CH<sub>2</sub>OH || H
-|-
-| [[LAE-32]] || H || CH<sub>3</sub> || [[Ethyl group|CH<sub>2</sub>CH<sub>3</sub>]] || H
-|-
-| [[Lysergic acid 2-butyl amide|LSB]] || H || CH<sub>3</sub> || CH(CH<sub>3</sub>)CH<sub>2</sub>CH<sub>3</sub> || H
-|-
-| [[Lysergic acid 3-pentyl amide|LSP]] || H || CH<sub>3</sub> || CH(CH<sub>2</sub>CH<sub>3</sub>)CH<sub>2</sub>CH<sub>3</sub> || H
-|-
-| [[Diallyllysergamide|DAL]] || H || CH<sub>3</sub> || [[Allyl|H<sub>2</sub>C=CH-CH<sub>2</sub>]] || Allyl|H<sub>2</sub>C=CH-CH<sub>2</sub>
-|-
-| [[Methylisopropyllysergamide|MIPLA]] || H || CH<sub>3</sub> || [[Isopropyl|CH(CH<sub>3</sub>)<sub>2</sub>]] || CH<sub>3</sub>
-|-
-| [[Ethylisopropyllysergamide|EIPLA]] || H || CH<sub>3</sub>  || CH(CH<sub>3</sub>)<sub>2</sub> || CH<sub>2</sub>CH<sub>3</sub>
-|-
-| [[Methylpropyllysergamide|LAMP]] || H || CH<sub>3</sub> || CH<sub>2</sub>CH<sub>2</sub>CH<sub>3</sub> || CH<sub>3</sub>
-|-
-| '''[[LSD]]''' / [[LSD|LAD]] || H || CH<sub>3</sub> || CH<sub>2</sub>CH<sub>3</sub> || CH<sub>2</sub>CH<sub>3</sub>
-|-
-| [[ETH-LAD]] || H || CH<sub>2</sub>CH<sub>3</sub> || CH<sub>2</sub>CH<sub>3</sub> ||  CH<sub>2</sub>CH<sub>3</sub>
-|-
-| [[PARGY-LAD]] || H || [[Propynyl|HC≡C−CH<sub>2</sub>]] ||  CH<sub>2</sub>CH<sub>3</sub> || CH<sub>2</sub>CH<sub>3</sub>
-|-
-| [[AL-LAD]] || H || H<sub>2</sub>C=CH-CH<sub>2</sub> ||  CH<sub>2</sub>CH<sub>3</sub> || CH<sub>2</sub>CH<sub>3</sub>
-|-
-| [[PRO-LAD]] || H || [[Propyl|CH<sub>2</sub>CH<sub>2</sub>CH<sub>3</sub>]] || CH<sub>2</sub>CH<sub>3</sub> || CH<sub>2</sub>CH<sub>3</sub>
-|-
-| [[CYP-LAD]] || H || [[Cyclopropyl|C<sub>3</sub>H<sub>5</sub>]] || CH<sub>2</sub>CH<sub>3</sub> || CH<sub>2</sub>CH<sub>3</sub>
-|-
-| [[BU-LAD]]  || H || [[Butyl|CH<sub>2</sub>CH<sub>2</sub>CH<sub>2</sub>CH<sub>3</sub>]]  ||  CH<sub>2</sub>CH<sub>3</sub> || CH<sub>2</sub>CH<sub>3</sub>
-|-
-| [[ALD-52]] || [[Acetyl|COCH<sub>3</sub>]] || CH<sub>3</sub> ||  CH<sub>2</sub>CH<sub>3</sub> || CH<sub>2</sub>CH<sub>3</sub>
-|-
-| [[MLD-41]] || CH<sub>3</sub> || CH<sub>3</sub> ||  CH<sub>2</sub>CH<sub>3</sub> || CH<sub>2</sub>CH<sub>3</sub>
-|-
-| [[LSM-775]] || H || CH<sub>3</sub> || colspan=2|[[Morpholine|CH<sub>2</sub>CH<sub>2</sub>-O-CH<sub>2</sub>CH<sub>2</sub>]]
-|-
-| [[LPD-824]] || H || CH<sub>3</sub> || colspan=2|[[Pyrrolidine|CH<sub>2</sub>CH<sub>2</sub>
-CH<sub>2</sub>CH<sub>2</sub>]]
-|-
-| [[LSD-Pip]] || H || CH<sub>3</sub> || colspan=2|[[Piperidine|CH<sub>2</sub>CH<sub>2</sub>
-CH<sub>2</sub>CH<sub>2</sub>CH<sub>2</sub>]]
-|-
-| [[Lysergic acid 2,4-dimethylazetidide|LA-SS-Az]] || H || CH<sub>3</sub> || colspan=2|CH<sub>2</sub>(CHCH<sub>3</sub>)<sub>2</sub>CH<sub>2</sub>
-|}
-==Pharmacology==
-Lysergamides are believed to produce their psychedelic effect primarily by partial agonism of [[Serotonin#The 5-HT System|5-HT<sub>2A</sub> receptors]].
 [[Category:Psychedelic]]